Cortisol Awakening Response (CAR)- Saliva
Saliva: Cortisol x4 and DHEA-S
The Cortisol Awakening Response ? also called CAR ? reveals more detailed clues that help in assessing adrenal hormone/HPA?Axis dysfunction. This testing is often useful for cases of PTSD, major depression, chronic fatigue syndrome and other severe stress conditions.
During a normal cortisol awakening response, adrenal hormone levels should increase 50% in the first 30 minutes after waking for the day and then begin to progressively drop through the afternoon and evening. To capture this response, three ? rather than one ? morning?saliva?collections are needed to properly chart the diurnal cortisol curve.
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6-Tube Collection:?Six cortisol collections in 24 hours is the most common method for assessing CAR. Start saliva collection within five minutes of waking for the day, followed by a second sample at 30 minutes, and a third sample at 60 minutes. The rest of the diurnal rhythm can be assessed at the normal time intervals ? noon, evening and night (shown below).
Description provided by ZRT LAB